Dr Jayden Lee Roberts

Lecturer

  • Biography

    Jayden Roberts completed his PhD in 2025 at the Australian National Phenome Centre, Murdoch University, where he investigated patient-centric blood microsampling as an alternative to conventional venepuncture. Using metabolic phenotyping approaches that combined nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry, he profiled lipoproteins, lipids, and other small molecules to assess the equivalence of finger-prick samples to venous blood for lipoproteins and inflammation markers. As part of this work, he developed a dried blood spot workflow capable of analysing over 400 lipids, which he successfully translated to a diabetic cohort, supporting future at-home metabolic health monitoring and precision medicine.

  • Teaching Areas

    Biomedical Science:

    • HLTH2210 Biochemistry
    • HLTH2300 Microbiology
    • HLTH3100 Immunology
    • HLTH3250 Infectious Diseases
    • HLTH3400 Human Genetics

  • Research Expertise and Supervision

    Research Interest

    • Patient-centric blood sampling for longitudinal and remote testing
    • High-throughput liquid chromatography-mass spectrometry analysis

    Supervision (Current)

    • 1 Honours student: Charlotte Preston "Validation of Dried Plasma Spot Microsamples for Comprehensive Lipid analysis"

    Supervision (Previous)

    • 2 Practicum students

  • Books

    Roberts JL, Ryan MJ, Whiley L, Gay M, Nambiar V, Holmes E, Nicholson JK, Wist J, Gray N,
    Lawler NG. Dried blood spot microsampling: a semi-quantitative 4D-lipidomics approach utilizing MetaboScape for enhanced lipid profiling. Bruker. 2025. Available online: https://www.bruker.com/en/applications/academia-life-science/metabolomics/lipidomics

  • Journal Articles and Proceedings

    • Roberts JL, Ryan MJ, Whiley L, Gray N, Gay M, Wist J, Nicholson JK, Holmes E, Lawler NG.
      Dried blood spot lipidomics in diabetes. bioRxiv. 2025. https://doi.org/10.1101/2025.05.28.656742
    • Roberts JL, Ryan MJ, Whiley L, Gay M, Nambiar V, Holmes E, et al. Dried blood spot
      microsampling: a semi-quantitative 4D-lipidomics approach using ultrahigh-performance liquid
      chromatography - high-resolution mass spectrometry (UHPLC - HRMS). Talanta. 2025:127677. doi:10.1016/j.talanta.2025.127677
    • Roberts JL, Whiley L, Gray N, Gay M, Nitschke P, Masuda R, et al. Rapid and self-
      administrable capillary blood microsampling demonstrates statistical equivalence with standard venous collections in NMR-based lipoprotein analysis. Anal Chem. 2024;96(11):4505-13. doi:10.1021/acs.analchem.3c05152
    • Roberts JL, Whiley L, Gray N, Gay M, Lawler NG. Advanced microsamples: current
      applications and considerations for mass spectrometry-based metabolic phenotyping pipelines. Sep. 2022;9(7):175-96. doi:10.3390/separations9070175

  • Conference Papers

    • Poster presentation | Roberts JL, Ryan MJ, Whiley L, Gray N, Gay M, Holmes E, Wist J, Nicholson JK, Lawler NG. Investigating the diabetic lipidome: a DBS-based high-resolution mass spectrometry approach. 21st Annual Conference of the Metabolomics Society – 2025 (Prague, Czechia).
    • Oral presentation | Roberts JL, Ryan MJ, Whiley L, Gray N, Gay M, Holmes E, Wist J, Nicholson JK, Lawler NG. Investigating the diabetic lipidome: a DBS-based high-resolution mass spectrometry approach. Inaugural AUS-oMicS conference – 2025 (Cairns, Australia).
    • Oral presentation | Roberts JL, Ryan MJ, Whiley L, Gay M, Nambiar V, Holmes E, Nicholson JK, Wist J, Gray N, Lawler NG. Dried blood spot microsampling: a semi-quantitative 4D-lipidomics approach using ultrahigh performance liquid chromatography - high resolution mass spectrometry (UHPLC-HRMS). Inaugural Health Futures Institute Higher Degree by Research Symposium – 2024 (Murdoch, Australia).
    • Poster presentation | Roberts JL, Ryan MJ, Whiley L, Gay M, Nambiar V, Holmes E, Nicholson JK, Wist J, Gray N, Lawler NG. Dried blood spot microsampling: a semi-quantitative 4D-lipidomics approach using ultrahigh performance liquid chromatography - high resolution mass spectrometry (UHPLC-HRMS). Inaugural Health Futures Institute Higher Degree by Research Symposium – 2024 (Murdoch, Australia).
    • Poster presentation | Roberts JL, Whiley L, Gray N, Gay M, Holmes E, Nicholson JK, Wist J, Lawler NG. High-resolution dried blood spot (DBS)-based 4D lipidomics platform. 6th Australian Lipid Meeting – 2024 (Brisbane, Australia).
    • Poster presentation | Roberts JL, Whiley L, Gray N, Gay M, Holmes E, Nicholson JK, Wist J, Lawler NG. Advancements in high-throughput dried blood spot-based 4D lipidomics. 25th International Mass Spectrometry Conference – 2024 (Melbourne, Australia).
    • Oral presentation | Roberts JL, Whiley L, Gray N, Gay M, Nitschke P, Masuda R, Holmes E, Nicholson JK, Wist J, Lawler NG. Rapid, self-administrable fingerprick ‘microsampling’ is functionally equivalent to standard venepuncture for NMR-based lipoprotein analysis. 20th Annual Conference of the Metabolomics Society– 2024 (Osaka, Japan).
    • Poster presentation | Roberts JL, Whiley L, Gray N, Gay M, Peng X, Holmes E, Nicholson JK, Wist J, Lawler NG. Application of dried blood spot microsampling for high-throughput four-dimensional trapped ion mobility spectrometry lipidomics. 72nd Annual Conference of the American Society for Mass Spectrometry –2024 (Anaheim, United States of America).
    • Poster presentation | Roberts JL, Whiley L, Gray N, Gay M, Nitschke P, Masuda R, Holmes E, Nicholson JK, Wist J, Lawler NG. Rapid and self-administrable capillary blood sampling is functionally equivalent to standard venous collections for NMR-based lipoprotein analysis. Australian Cardiovascular Alliance (ACvA) Flagship Precision Medicine Symposium – 2023 (Melbourne, Australia).
    • Oral presentation | Roberts JL, Whiley L, Gray N, Gay M, Nitschke P, Masuda R, Holmes E, Nicholson JK, Wist J, Lawler NG. Rapid, self-administrable fingerprick ‘microsampling’ is functionally equivalent to standard venepuncture for NMR-based lipoprotein analysis. Australian National Phenome Centre / Centre for Computational & Systems Medicine Showcase – 2023 (Murdoch, Australia).
    • Poster presentation | Roberts JL, Whiley L, Gray N, Gay M, Nitschke P, Masuda R, Holmes E, Nicholson JK, Wist J, Lawler NG. Rapid, self-administrable fingerprick ‘microsampling’ is functionally equivalent to standard venepuncture for NMR-based lipoprotein analysis. Australian National Phenome Centre / Centre for Computational & Systems Medicine Showcase – 2023 (Murdoch, Australia).
    • Oral presentation | Roberts JL. Microsampling: applications for sample miniaturisation in metabolic phenotyping. Murdoch University Three-Minute Thesis Final – 2023 (Murdoch, Australia).
    • Oral presentation | Roberts JL. Microsampling: applications for sample miniaturisation in metabolic phenotyping. Murdoch University College of Health and Education Three-Minute Thesis Competition – 2023 (Murdoch, Australia).
    • Oral presentation | Roberts JL, Whiley L, Gray N, Gay M, Holmes E, Nicholson JK, Wist J, Lawler NG. High-resolution DBS-based lipidomics platform. 29th Biennial Conference of the Australian and New Zealand Society for Mass Spectrometry – 2023 (Wollongong, Australia).
    • Poster presentation | Roberts JL, Whiley L, Gray N, Gay M, Holmes E, Nicholson JK, Wist J, Lawler NG. Quick andself-administrable capillary blood sampling compares with phlebotomist's venous collections for NMR-based lipoprotein molecular phenotyping. Science on the Swan Conference – 2023 (Perth, Australia).

  • In the Media

    • Television | Channel 9 News National – Breakfast: New way to monitor heart health. 2024, February 22. Available online: https://tinyurl.com/2kz6mbjr
    • Television | Channel 9 News Perth – 6PM: New way to monitor heart health. 2024, February 21. Available online: https://www.facebook.com/9NewsPerth/videos/7126610184120986/
    • Radio | ABC Canberra – Drive: Breakthrough in blood testing for heart disease. 2024, February 21. Available online: https://www.abc.net.au/listen/programs/canberra-drive/canberra-drive/103474356
    • Radio | ABC Perth – Mornings: Breakthrough in blood testing for heart disease. 2024, February 21. Available online: https://www.abc.net.au/listen/programs/perth-mornings/mornings/103470706
    • News Article | Self-administered blood test shows promise for checking heart health. 2024, February 21. Available online: https://medicalxpress.com/news/2024-02-blood-hearthealth.html
    • News Article | Revolutionizing cardiovascular risk assessment. 2024, February 21. Available online: https://medriva.com/heart-disease/revolutionizing-cardiovascular-risk-assessment-self-administered-blood-test/
    • Press Release | Check your heart’s health with the prick of a pin. 2024, February 20. Available online:
      https://www.murdoch.edu.au/news/articles/check-your-heart-s-health-with-the-prick-of-a-pin

  • Professional Affiliations

    Australia, New Zealand, and South East Asia Task Group Lead
    Patient Centric Sampling Interest Group (PCSIG)
    January 2025 – Present

    Online Presence Task Group Lead and Committee Member
    Early Career Member Network of the Metabolomics Society (EMN MetSoc)
    September 2024 – Present

    'Data to discovery: A multi-omics masterclass' Conference Workshop Organising Committee Member
    Inaugural AUS-oMicS conference in 2025 (Cairns, Australia)
    August 2024 – May 2025

    Early Career Research Subcommittee Representative
    Australian and New Zealand Metabolomics Society (ANZMetSoc)
    May 2024 – Present

    Symposium Organising Committee Member
    Inaugural Health Futures Institute Higher Degree by Research Symposium (Murdoch University)
    2024

    Student Member
    Australian and New Zealand Society for Mass Spectrometry (ANZSMS)
    May 2021 – Present

  • Awards

    • Grant | Theo Murphy Initiative (Australia) 2024 – 2025 Amplify Activity Grant recipient. Amount: $11,900 – for hosting a short course on multi-omic data handling 'Data to discovery: A multi-omics masterclass' at the Inaugural AUS-oMicS conference – 2025 (Cairns, Australia).
    • Runner-Up Poster Presentation | Inaugural Health Futures Institute Higher Degree by Research Symposium – 2024 (Perth, Australia).
    • Registration Award | International Mass Spectrometry Conference (IMSC) Student Registration Award to attend the 25th International Mass Spectrometry Conference – 2024 (Melbourne, Australia).
    • Travel Award | Australian and New Zealand Metabolomics Society (ANZMetSoc) Travel Award to attend the 20th Annual Conference of the Metabolomics Society – 2024 (Osaka, Japan).
    • Travel Award | Murdoch University Graduate Research School International Conference Travel Award – 2024 (Murdoch, Australia).
    • Best Poster | Australian Cardiovascular Alliance (ACvA) Flagship Precision Medicine Symposium – 2023 (Melbourne, Australia).
    • Travel Award | Australian Cardiovascular Alliance (ACvA) Flagship Precision Medicine Symposium – 2023 (Melbourne, Australia).
    • Runner-Up Presentation Award | Australian National Phenome Centre / Centre for Computational & Systems Medicine Showcase – 2023 (Murdoch, Australia).
    • Best Presentation | Three-Minute Thesis (3MT), Murdoch University, School of Health and Education – 2023 (Murdoch, Australia).
    • Publication Award | Most-Viewed Paper of 2022 in Separations MDPI for "Advanced microsamples: Current applications and considerations for mass spectrometry-based metabolic phenotyping pipelines".
    • Travel Award | Australian and New Zealand Society for Mass Spectrometry (ANZSMS) Student Travel Bursary to attend the 29th Biennial Conference of the Australian and New Zealand Society for Mass Spectrometry – 2023 (Wollongong, Australia).
    • Scholarship | Murdoch University and Bruker Daltonics Joint Research Training Program (RTP) Industry Scholarship.
    • Scholarship | Murdoch University Commonwealth Supported Research Training Program (RTP) 'fees offset' Scholarship.

  • Other

    • Preprint | Roberts JL, Ryan MJ, Whiley L, Gray N, Gay M, Wist J, Nicholson JK, Holmes E, Lawler NG. Dried blood spot lipidomics in diabetes. bioRxiv. 2025. Manuscript Id: 2025/656742
    • Preprint | Roberts JL, Ryan MJ, Whiley L, Gay M, Nambiar V, Holmes E, Nicholson JK, Wist J, Gray N, Lawler NG. Dried blood spot microsampling: a semi-quantitative 4D-lipidomics approach using ultra high performance liquid chromatography - high resolution mass spectrometry (UHPLC-HRMS). SSRN. 2024. doi:10.2139/ssrn.5029593
    • Preprint | Roberts JL, Whiley L, Gray N, Gay M, Nitschke P, Masuda R, Holmes E, Nicholson JK, Wist J, Lawler NG. Rapid and self-administrable capillary blood microsampling demonstrates statistical equivalence with standard venous collections in NMR-based lipoprotein analysis. ChemRxiv. 2023. doi:10.26434/chemrxiv-2023-66xp5
    • Journal Cover Art | Roberts JL. Cover art for Analytical Chemistry: Microsampling redefines lipoprotein analysis: a few drops of blood are as informative as the oceans traditionally drawn through venepuncture. ACS Publications. 2024. https://pubs.acs.org/toc/ancham/96/11
    • Encyclopedia Entry | Roberts JL, Whiley L, Gray N, Gay M, Lawler NG. Advanced microsamples. Encyclopedia. 2022. Available online: https://encyclopedia.pub/entry/25228
    • Encyclopedia Entry | Roberts JL, Whiley L, Gray N, Gay M, Lawler NG. Approaches to microsample collections. Encyclopedia. 2022. Available online: https://encyclopedia.pub/entry/25224
    • Preprint | Roberts JL, Whiley L, Gray N, Gay M, Lawler NG. Advanced microsamples: current
      applications and considerations for mass spectrometry-based metabolic phenotyping pipelines. Preprints. 2022. doi:10.20944/preprints202206.0040.v1