Maria Kadyrov

MSc, BSc
Lecturer

Email: maria.kadyrov@nd.edu.au

  • Biography

    Maria is a Lecturer in Biomedical Science and a final-year PhD candidate specialising in lipidomics, cognition, and lifestyle modification in the context of ageing. She holds a Bachelor of Science in Molecular Genetics from Curtin University and a Master of Forensic Science from Murdoch University, reflecting her broad academic foundation and interests in genetics and forensic applications.

    Her PhD research aims to understand the lipidomic signatures that characterise metabolic and cognitive health in older adults, with a focus on molecular pathways that may be modified through lifestyle interventions such as structured aerobic exercise. To achieve this, Maria applies computational biology and machine learning approaches (e.g. predictive modelling, network analysis, supervised and unsupervised learning) to analyse high-dimensional NMR- and MS-based metabolomics datasets. These methods allow her to map lipidomic patterns associated with traits such as adiposity, cognition, and cardiorespiratory fitness.

    Ultimately, Maria’s work seeks to uncover modifiable biological targets to inform dementia prevention strategies and promote healthy brain ageing.

  • Teaching Areas

    • HLTH1150 - Academic Research and Writing
    • HLTH3400 - Human Genetics
    • HLTH1030 - Anatomy and Physiology of Body Systems

  • Research Expertise and Supervision

    Research Expertise:

    • Metabolomics & Lipidomics (1H-NMR spectroscopy, UHPLC-MS/MS)
    • Cognition & Ageing (dementia prevention)
    • Lifestyle modification (body composition analysis, cardiorespiratory fitness)
    • Computational Biology (biostatistics, machine learning)

    Supervision:

    • 2022 Masters (ForensicScience): A. Hamilton - A Metabolomics Approach for the Potential Characterisation of Salivary Fatigue Biomarkers for Roadside Testing by Police

  • Journal Articles and Proceedings

    • Kadyrov, M., Whiley, L., Brown, B., Erickson, K. I., & Holmes, E. (2022). Associations of the Lipidome with Ageing, Cognitive Decline and Exercise Behaviours. Metabolites, 12(9), 822. https://doi.org/10.3390/metabo12090822
    • Hamilton, A., Whiley, L., Kadyrov, M., & Chapman, B. (2025). Forensic biomarker discovery: Utilising metabolomics to elucidate prospective fatigue biomarkers for eventual roadside detection. Science & Justice: Journal of the Forensic Science Society, 65(4), 101278. https://doi.org/10.1016/j.scijus.2025.101278
    • Kadyrov, M., Whiley, L., Brown, B., Erickson, K. I., & Holmes, E. (2025). Arachidic Acid Carrying Phosphatidylglycerol Lipids Mediate the Relationship Between Central Adiposity and Cognitive Function in Older Adults (Under Review)
    • Kadyrov, M., Whiley, L., Grant St James, A., Minaee, N., Masuda, R., Lee, A., Hui, J., Hunter, M. L., Zhu, K., Beilby, J. P., Yeap, B. B., Erickson, K. I., Lodge, S., Wist, J., Brown, B., Nicholson, J. K., & Holmes, E. (2025). Weighted correlation network analysis of plasma lipidome identifies distinct patterns linked to lipoprotein subfractions and adiposity phenotypes (Under Review)

  • Conference Papers

    • Kadyrov, M., Whiley, L., Brown, B., Erickson, K. I., & Holmes, E. (2022). The Effects of Moderate and High Intensity Aerobic Exercise on Lipid and Lipoprotein Metabolism in Cognitively Normal Older Australians: Data from the IPAC study. Science on the Swan; Perth, Australia
    • Kadyrov, M., Whiley, L., Erickson, K. I., Holmes, E., & Brown, B., (2022). The Effects of Aerobic Exercise on Lipids Associated with Hippocampal Volume. Symposium of Western Australian Neuroscience; Perth, Australia
    • Kadyrov, M., Whiley, L., Erickson, K. I., Holmes, E., & Brown, B., (2023). The Effects of Aerobic Exercise on Lipids and Lipoproteins Associated with Hippocampal Volume. Alzheimer’s Association International Conference; Amsterdam, Netherlands
    • Kadyrov, M., Whiley, L., Brown, B., Erickson, K. I., & Holmes, E. (2024). The Plasma Lipidome is Not Associated with Cognition and Cardiorespiratory Fitness in Cognitively Normal Older Australians. Metabolomics Society International Conference; Osaka, Japan
    • Kadyrov, M., Whiley, L., Brown, B., Erickson, K. I., & Holmes, E. (2024). Associations of Plasma Lipid Correlation Network Profiles and Global Cognition in Cognitively Normal Older Adults. Australian Neuroscience Society Conference; Perth, Australia

  • Awards

    • Emerging Researchers in Ageing Travel Scholarship ($8000) - Funded an international research internship at Imperial College of London, UK (2023)
    • Flexible Talent Mobility Award ($1000) - Funded Maria’s participation in the “Tools & Technologies in Ageing Research” ECR Summer School at Queen’s University Belfast, Northern Ireland (2023)