Professor Gerard Hoyne 

BSc(Hons), PhD, GCUT
Associate Dean Research – Faculty Medicine, Nursing and Health Sciences

Email: gerard.hoyne@nd.edu.au
Phone: 9433 0236

  • Biography

    Gerard Hoyne joined Notre Dame in 2009 and was appointed the Associate Dean of Research in the School of Health Sciences until 2020 and was appointed to the position of  Associate Dean of Research for the Faculty of Medicine, Nursing, Midwifery and Health Sciences in 2021. Gerard completed his BSc(Hons) and PhD at The University of Western Australia and has previously worked at Imperial College in London, the University of Edinburgh in the United Kingdom and the Australian National University within the field of immunology. His research work has investigated how the immune system regulates immune responses to self and foreign proteins. This has important implications in the development of autoimmune diseases such as allergies and diabetes.

    He has gained research funding both in Australia and overseas over the last 20 years. He has co-authored over 70 scientific manuscripts and has presented his work at national and international scientific conferences. He was a co-founding scientist of a biotechnology company that was established in Cambridge in the UK and is a named inventor on eight international patents that have been granted.

    • Chair of the UNDA Human Research Ethics Committee
    • Member Raine Awards and Prizes Advisory Committee

  • Teaching Areas

    Infectious Disease, Immunology and Microbiology

  • Research Expertise and Supervision

    I have supervised 13 PhD , 5 Masters and 26 Honours students to completion. I currently supervise 3 PhD, 1 Masters and 1 Honours student.

    I have reviewed grants for the Medical Research Council UK, The Wellcome Trust UK, Diabetes Australia Research Trust, Leukaemia Foundation, Human Frontiers Science Project, St Vincent Medical Research Foundation, Sydney Medical Research Foundation, Multiple Sclerosis Society, Diabetes Australia Research Trust, FWO Flanders Belgium.

    Reviewed papers for the following Journals: Nature Immunology, Immunology and Cell Biology, PLOS One, Immunology, Leukemia Research, International Archives of Allergy and Clinical Immunology, Febbs Letters – Immunology, Clinical and Developmental Immunology, Molecular and Cellular Immunology, American Journal of Clinical Immunology, International Journal of Molecular Sciences, Journal of Clinical and Cellular Immunology.

    Membership in Editorial Boards

    • Higher Education Studies 2016 -present
    • American Journal of Clinical and Experimental Immunology 2012 – present
    • Frontiers in Cellular and Infection Microbiology 2022 - present

  • Book Chapters

    • Hoyne GF, Alessandrini, J and Fellman, M. 2016. Doctoral education for the future: through the looking glass. In Emerging Directions in Doctoral Education.  Innovations in Higher Education Teaching and Learning (IHETL) Ed Patrick Blessinger, Emerald Publishing Group. Vol 6: 21-38. ISSN: 2055-3641/doi:10.1108/S2055-364120160000006010.
    • Jarman, E.R., Hoyne, GF., and Lamb, JR. Tolerance to inhaled antigen. 2003. In  The Immunological Basis of Asthma. Lambrecht, BM, Hoogsteden, HC and Diamant Z. (Eds), Series title: Lung Biology in Health and disease. p221-241. CRC Press Print ISBN: 978-0-8247-0882-5, eBook ISBN: 978-0-8247-4764-0.
    • Hetzell, C., Hoyne, G.F., Kristensen, N.M., Bourne, T., Tsitoura, D., and Lamb J.R.Peptide-Mediated Regulation of Allergic Diseases. 1996. In MHC Molecules: Expression, Assembly and Function. Ed. Urban R.G. and Chicz, R.M. RG Landes Company, Springer US. Chapter 16, p261-279. DOI: 10.1007/978-1-4684-6462-7_16. https://link.springer.com/chapter/10.1007%2F978-1-4684-6462-7_16#page-1
    • Hoyne G., Bourne T., Kristensen N., Hetzel C. & Lamb J. 1995 Peptide Handling by the Immune system. In Progerss in Allergy and Clinical Immunology. Johansson SG (Ed) Progress in Allergy and Clinical Immunology Series 3: 215-219.
    • O’Hehir, R.E., Hoyne GF, Lamb, JR. 1994. Molecular characterization and immune recognition of allergenic peptides. In Molecular and cellular biology of the allergic response. Levison, A.I. and Paterson Y. (Eds). Series title: Clinical Allergy and Immunology, Kaliner, M.A. (Series Ed.). Marcel Dekker Inc NY p411-432.

  • Journal Articles and Proceedings

    • Puca J. Hoyne GF. 2017. Microbial dysbiosis and disease pathogenesis of endometriosis, could there be a link? Allied Journal of Medical Research 1 (1): 1-9.
    • Jones B and Hoyne GF. 2017. The role of the innate and adaptive immunity in exercise induced muscle damage and repair. J Clin Cell Immunol 8: 482. doi:10.4172/2155-9899.1000482http://www.alliedacademies.org/allied-journal-of-medical-research/
    • Benn N and Hoyne GF. 2018. Role of the gut microbiome as a natural adjuvant for vaccines. Immunotherapy (Los Angel), 4:2.  DOI: 10.4172/2471-9552.1000150.
    • Hoes, M and Hoyne, GF. 2018. Key changes to the H7N9 Influenza virus that facilitated human adaptation. Clinical Immunology Research 1 (2) 1-6.
    • Hoyne, GF., Elliott, H., Mutsaers, SE. and Prele, CM. 2017. Idiopathic Pulmonary Fibrosis and a role for autoimmunity Immunol Cell Biol; 95(7):577-583.doi:10.1038/icb.2017.22.
    • Luckin, K., Cripps, A. Merrells, R and Hoyne GF. 2018. Strength Training in Long-Distance Triathletes: Barriers and Characteristics. J Stength Cond Res (doi: 10.1519/JSC.0000000000002716).
    • Raman A., Peiffer, JJ, Hoyne GF, Lawler, NG and Fairchild, TJ. 2018 Effect of exercise on acute postprandial glucose concentrations and interleukin-6 responses in sedentary and overweight males Appl Physiol Nutr Metab. 2018 Dec;43(12):1298-1306. doi: 10.1139/apnm-2018-0160.
    • Piggott, B., Chivers, P, Muller S and Hoyne GF. 2019. Is Sports Science answering the call for interdisciplinary research? A systematic review. Eur J Sports Science. 19 (3) 267-286. (Doi: https://doi.org/10.1080/17461391.2018.1508506)
    • Piggott, B., Muller, S., Chivers, P, Cripps, A., and Hoyne GF. 2019. Small-sided games can discriminate perceptual-cognitive-motor capability and predict disposal efficiency in match performance of skilled Australian footballers. J Sports Sci. 37(10):1139-1145. doi: 10.1080/02640414.2018.1545522
    • Piggott, B., Muller, S., Chivers, P, Cripps, A., and Hoyne GF. 2019 Coach rating combined with small-sided games provides further insight into mental toughness in sport. Front Psychol. 10: 1552 doi: 10.3389/fpsyg.2019.01552.
    • Luckin, K., Cripps, A. Landers, G., Merrells, R Bulsara, M., and Hoyne GF. 2019. Reliability and validity testing of a modified triathlon test for measurements of performance economy for triathletes Journal of Science and Cycling 8 (3) 25-32.  DOI : 10.28985/1920.jsc.05.
    • Piggott, B., Muller, S., Chivers, P, Cripps, A., and Hoyne GF. 2020 Interdisciplinary sport research can better predict competition performance, identify individual differences and quantify task representation. Front. Sports Act. Living 2:14. doi: 10.3389/fspor.2020.00014
    • Mutsaers, S., Pixley, FJ., Prele, CM. and Hoyne GF. 2020. Mesothelial and immune cell  interactions.  Current Opinion Immunology 64, 88-109. https://doi.org/10.1016/j.coi.2020.04.005
    • Bissett A and Hoyne GF. 2020. Evolution and adaptation of the avian H7N9 Virus into the human host. Microorganisms 8(5), 778; https://doi.org/10.3390/microorganisms8050778 .
    • Hoyne, GF and Prele, CM. 2020. Special Feature: Immunopathobiology of chronic lung disease". Clin Trans Immunol. 9: e1170.  doi: 10.1002/cti2.1170
    • Myles, T., Hoyne, GF., Knight DA, Fear, M., Mutsaers SE. and Prele, CM. 2020. The contribution of animal models to understanding the role of the immune system in human IPF. Clin Trans Immunol  9:e1153.  DOI: https://doi.org/10.1002/cti2.1153.
    • Luckin-Baldwin, KM., Badenhorst, Claire E., Cripps, Ashley J., Landers, Grant J., Merrells, Robert J., Bulsara, MK., & Hoyne. GF. (2021). Strength training improves exercise economy in triathletes during a simulated triathlon. International Journal of Sports Physiology and Performance. 16(5) 663-673. https://doi.org/10.1123/ijspp.2020-0170.
    • van den Buuse M., Halley P. and Hoyne GF. 2021. Behavioural phenotyping of thunder mice with a hypomorphic mutation of heterogeneous nuclear ribonuclear protein L-like (hnRNPLL) and reduced T cell function. Neuroscience Letters 2021 Jan 1;740:135469.  doi:10.1016/j.neulet.2020.135469).
    • Yabas, M, Yazicioglu, YF., Hoyne GF, Goodnow CC and Anders A. 2021. Loss of hnRNPLL-dependent splicing of Ptprc has no impact on B cell development, activation and terminal differentiation into antibody secreting cells.  Immunol Cell Biol; 99(5):532-541. doi: 10.1111/imcb.12433.
    • Bissett A and Hoyne GF. 2021. An outbreak of highly pathogenic avian influenza (H7N7) in Australia and the potential for novel Influenza A viruses to emerge. Microorganisms  9 (8) 1639. doi.org/10.3390/microorganisms9081639.
    • Wu, Z, Sweet R.A. Hoyne GF., Simoneovic CJ and Parish CR. Acute T cell driven inflammation required the endoglycosidase Heparanase -1 from multiple cell types. Int J Mol Sci 2022, 23, 4625. https://doi.org/10.3390/ ijms23094625.
    • Prêle CM, Pearce DR, Miles T, O’Donoghue R, Barrett L, Birnie K, Lucas A, Baltic, S, Fear M, Ernst M, Rinaldi C, Laurent GJ, Knight DA, *Hoyne G, McAnulty R, *Mutsaers SE. Circulating plasmablasts, B memory and lung resident plasma cells phenotypically characterise pulmonary fibrosis. Eur Resp J  Jul 7:2101469. doi: 10.1183/13993003.01469-2021
    • Luckin, K., Cripps, A. Landers, G., Merrells, R Bulsara, M., and Hoyne GF. 2022. Strength Training for Long-Distance Triathletes: Theory to Practice. Strength & Conditioning Journal 44, 1 -14 doi: 10.1519/SSC.0000000000000660.
    • Muller, S., Morris-Binelli K, Piggott B., Hoyne G., Christensen, W., Fadde P, Zaichowsky, L., Brenton, J. 2022 Attributes of expert anticipation should inform design of simulators to accelerate learning and transfer of skill. J Sports Science, 10.1007/s40279-022-01735-7.
    • Raman A., Peiffer, JJ, Hoyne GF, Lawler, NG and Fairchild, TJ 2023 "Exercise-induced responses in matrix metalloproteinases and osteopontin are not moderated by exercise format in males with overweight or obesity." European Journal of Applied Physiology, (accepted).

  • Conference Papers

    • McNaught, K. & Hoyne, G. (2011) Mathematics for first year success. Proceedings of the 14th Pacific Rim First Year in Higher Education Conference. Retrieved from http://www.fyhe.com.au/past_papers/papers11/FYHE-2011/index.html.
    • McNaught, K. & Hoyne, G. (2012) Predicting a student’s success in Health Sciences based on their academic writing skills. International First Year in Higher Education Conference. Retrieved from http://www.fyhe.com.au/past_papers/papers12/Papers/3A.pdf.
    • McNaught, K. & Hoyne, G. (2013). Testing program reveals deficient mathematics for health science students commencing university. In Design, develop, evaluate: The core of the learning environment. Proceedings of the 22nd Annual Teaching Learning Forum, 7-8 February 2013. Perth: Murdoch University. http://otl.curtin.edu.au/professional_development/conferences/tlf/tlf2013/refereed/mcnaught.html.
    • Hoyne, G. and McNaught K. (2016) Changing practices to better support first-year health Science students. Refereed paper STARS Conference Perth 2016. Retrieved from http://unistars.org/papers/STARS2016/01A.pdf
    • Raman, A., Peiffer, J., Hoyne G., Kanaley, J. and Fairchild T.  (2016) Acute post-exercise glucose disposal: exploring the role for exercise intensity in overweight/obese Males. Med Sci Sports Exerc. 2016 May;48(5 Suppl 1):821. doi: 10.1249/01.mss.0000487462.89727.86.

  • Professional Affiliations

    • Member of the Australian Society of Immunology 2002- present.
    • Board member ATEM 2018-2020
    • Chair ATEM Western Regional Organizing Committee 2018 –2020
    • Member of the Australian Tertiary Education Management (ATEM) 2012 – onwards
    • Member of the ATEM Western Regional Organizing Committee 2012 - onwards

  • Community Engagement

    • Member Raine Awards and Prizes Advisory Committee 2018-2025
    • Member of the MRFF Grant review panel EMCR 2022.
    • Member of the NH&MRC Grant Review Panel (Immunology) 2010, 2017, 2018.
    • Chair – External Scientific Advisory Board Systems and Intervention Research Centre for Health (SIRCH), School of Health Sciences, Edith Cowan University 2015- 2018​
    • Member of the Organizing Committee for the Australasian Society for Immunology Annual Conference, Perth 2010 and Canberra 2008.
    • Coordinator of the Postgraduate Student Workshop ASI Meeting, Perth.2010.
    • ACT Councillor Australasian Society for Immunology 2008-2009.
    • Coordinator of the Postgraduate Student Workshop ASI Meeting, Canberra 2008.
    • Organizer- World Day of Immunology Celebrations- Canberra 2008 & 2009

  • Awards

    • 1996 Pharmacia Fellowship.
    • 1989 Australian Society of Immunology student travel award, Adelaide.
    • 1989 UWA PhD Scholarship

  • Other

    • Gerard has examined 15 PhD theses and 3 Masters Theses from Australian and European universities.